Chronic inflammation of the mucosa of the sigmoid colon is not an important disease. It is relatively slow to treat, but the condition tends to recur and is difficult to cure. Chronic inflammation of the mucosa of the sigmoid colon is a kind of enteritis. It is easy to attack, and has a great relationship with long-term unhealthy dietary habits, patients can appear abdominal distension, abdominal pain, diarrhea and other symptoms, general colonoscopy and enteroscopic mucosal biopsy can be clear, after active, reasonable treatment, can effectively relieve the condition. Daily diet is recommended to be light and easy to digest. Eat more fresh vegetables and fruits, and avoid spicy and stimulating foods. Don’t eat food with too hard texture, so as not to damage the intestinal mucosa. Quit smoking and drinking. Pay attention to rest, appropriate physical exercise, form a good habit. In addition, you can take oral antibiotics such as clarithromycin or mucosal protective agent teprenone to improve inflammation, and you can also take drugs to regulate intestinal function, such as bifidobacteria, etc. for treatment. When suffering from chronic inflammation of the mucosa of the sigmoid colon, the intestinal mucosa is already damaged. It is recommended to consult a doctor in time, under the guidance of the doctor reasonable choice of drugs for comprehensive treatment, do not take medication without authorization, to avoid aggravating the condition.