How long can you run after ankle sprain can not be generalized, it should be determined according to the severity of the injury and the degree of recovery from treatment, mild injuries need 2 weeks, severe cases such as bone fracture need 10~12 weeks after the ankle injury can be recovered, and gradually resume walking and running. 1. Mild injury: if the ankle is mildly sprained, without bone and ligament damage, early rest and braking, proper treatment, swelling can be reduced after walking on the ground, 2 weeks later, according to the pain can be appropriate jogging activities. 2. Ligament injury: after examination, it is determined that there is ligament tear or rupture, after 4~8 weeks of conservative treatment or surgical treatment, you can walk on the ground with weight bearing, and gradually move around, and you can run after complete recovery. 3. Ankle fracture: If ankle fracture is diagnosed, mild cases need to be fixed by plaster or brace, and serious cases should choose surgery for internal fixation treatment, which usually takes 10~12 weeks for the bone to heal, and the fracture can be completely healed by taking photos for review, and then you can walk on the ground with weight bearing, and gradually resume running. Patients with sprained ankles are advised to actively seek medical attention and follow the doctor’s instructions for targeted treatment after a clear diagnosis through examination.