The 12-week folic acid genetic test is not necessary for every pregnant woman, depending on whether she has a family genetic history of problems. 1. Pregnant women have a family genetic history: If someone in the family of a pregnant woman has a disease of folic acid metabolism, then the 12-week folic acid genetic test is very necessary. The doctor can determine whether to continue taking folic acid and the dose of folic acid according to the results of the test. 2. Pregnant women do not have a family genetic history: If there is no folic acid metabolism disease in the family of pregnant women, and pregnant women in the 12th week of pregnancy to comply with the doctor’s instructions to take folic acid, then the folic acid gene test does not have to be done. Therefore, the 12-week folic acid genetic test is not a prescribed program of the maternity test, and whether a pregnant woman needs to do it depends on the actual situation of the individual. It is advisable to consult the attending doctor and follow the doctor’s professional advice to choose a program that suits your needs.