Pimples, or acne, are usually caused by Propionibacterium acnes infection, abnormal keratinization of hair follicle openings, and exuberant sebaceous gland secretion. Erythromycin ointment is an antibiotic, which can have an inhibitory effect on Propionibacterium acnes. When acne lesions are broken, erythromycin ointment can be applied under the guidance of a doctor. If acne breakouts are prone to skin infections, it is recommended to seek prompt medical attention. First, disinfection should be carried out, iodine povidone can be used to rub the breakout area and the surrounding skin, to clean the skin surface dirt, thus reducing the chance of wound infection. After disinfection, you can apply medication to the acne breakout, such as erythromycin ointment and mupirocin ointment. If there are symptoms such as redness, swelling and pain, infection may occur, with the exception of antibiotic ointment if the symptoms are severe, and oral antibiotics such as clindamycin and doxycycline under the guidance of a doctor. The appearance of acne should be timely consultation, follow the doctor’s instructions for treatment, avoid self-medication, so as not to cause discomfort.