Cranial defect is a very common problem in neurosurgery. Cranial defect not only reduces the value of the face, but also causes a series of cranial defect syndrome, which is very painful for patients. Therefore, when skull defect occurs, you should go to a regular hospital for skull repair surgery as soon as possible to restore the integrity of the skull and avoid further damage. However, the choice of repair material is very critical in the skull repair surgery. At present, many hospitals commonly use titanium mesh material, which is much more advanced than various materials in the past and the price is not high. However, titanium mesh material has some unavoidable problems, such as possible postoperative infection and rejection; affecting postoperative CT MRI and artifacts; poor insulation performance, which can be sensitive to external hot and cold reactions; large scalp irritation, and the risk of material exposure. Therefore, titanium mesh material is not yet particularly ideal for cranial bone repair material, compared to the new polyetheretherketone peek material which is more accepted by patients today. The price of PEEK is higher than that of titanium mesh, but it has many advantages in terms of hardness, elasticity, stability, and heat transfer that are comparable to autologous cranial bone, and through precise three-dimensional shaping, it can truly restore the anatomical structure of the skull and is ideal for skull repair surgery. However, PEEK is not commonly used in China, and we are the only hospital in the country where PEEK is available for treatment. Our team has performed many skull repair surgeries, and we are constantly improving and upgrading our technology and optimizing the design of our materials, and have successfully introduced the concept of aesthetic plastic surgery to perform comprehensive PEEK skull repair plastic surgery, which has yielded very good results and is highly recognized and chosen by patients.