Rabies is a zoonotic infectious disease, with the main sources of infection being sick dogs, cats, pigs and other animals. In addition, wild animals such as raccoons and bats that carry the rabies virus are also contagious. Rabies is less likely to be transmitted from person to person. Rabies can also be called hydrophobia. As an acute infectious disease, its clinical manifestations include fear of water, fear of the wind, excessive excitement, fear of light, and pharyngeal muscle spasms. The main modes of transmission of rabies virus include scratch transmission, bite transmission, sick dog slaughter transmission, aerosol transmission, and organ transplantation transmission. After a person is infected with rabies virus, the virus first invades the peripheral nerves around the wound and then gradually infects the central nerves. At that stage, human saliva does not contain rabies virus, even if biting or scratching others, there will be no infection. Man-made rabies infection, on the other hand, can only occur after the clinical symptoms of rabies have appeared. Therefore, human-to-human rabies infections are rare in clinical practice. The case fatality rate of rabies is 100% and prevention is the mainstay at this stage. If you are bitten or scratched by a dog, you should take preventive treatment through rabies vaccination within 24 hours without delay to prevent serious consequences.