The most correct time to give the medication three times a day is every eight hours. If the patient is hospitalized, the medication must be given strictly according to this time to achieve the normal blood concentration and also to keep the blood concentration stable. However, if you take the medication at home, and the medical prescription does not strictly require you to take the medication once every eight hours, you can adjust the time of taking the medication on your own, for example, if you take the first medication at 8:00 am, you can take the second medication from 2:00 pm to 4:00 pm, and then take the third medication before going to bed at night. If there are no special requirements, it is recommended to take the medication after taking food by mouth before going to bed at night to avoid greater stimulation to the gastrointestinal tract.