The main topical painkillers for knee pain are three kinds: 1, opioid drugs, such as fentanyl transdermal patch, the drug is applied to a relatively flat skin location, the drug lasts for about 72 hours, mainly for knee pain is more intense, intolerable pain, after the patch with the palm of the hand pressure for 30 seconds. 2, Fotalin cream, also called diclofenac sodium cream, the drug belongs to the non-steroidal It is a non-steroidal anti-inflammatory and analgesic drug, which can play an anti-inflammatory and analgesic role after application, and can reduce local inflammatory edema and reduce inflammatory irritation. 3, blood activation, swelling and pain relief creams, such as wound pain relief, blood activation and pain relief cream, Wan Tong tendon and bone paste, can effectively improve blood circulation. In addition, you can also choose to apply magnetic therapy paste, which can also accelerate local blood circulation after application, allowing the surrounding soft tissues to become relaxed and reduce the stimulation of metabolic products on peripheral nerves, which can also play a role in pain relief.