Walking and feeling tired 4 months after partial resection of renal clear cell carcinoma may be caused by tumor metastasis to lumbar vertebrae, lumbar muscle strain, damage to subcutaneous nerve of surgical incision. 1. Tumor metastasis: clear cell carcinoma of kidney metastasized to lumbar vertebrae and invaded lumbar vertebrae or pressed lumbar nerves, which will cause lumbar pain and discomfort and tiredness. It is necessary to go to the hospital for examination in time to find out whether there is metastasis or not. 2. Lumbar muscle strain: lumbar muscle strain caused by lumbar sprain or long-term incorrect posture of postoperative patients will cause lumbar pain and discomfort when walking; correcting bad posture and wearing waist protector when necessary can alleviate the symptoms. 3. Damage to subcutaneous nerves of surgical incision: damage to subcutaneous nerves caused by surgical process will cause postoperative lumbar discomfort; if the nerves are not completely broken, they can be recovered slowly, and generally it will not seriously affect patients’ quality of life, so no special treatment is needed. There are many other reasons why patients feel tired when walking 4 months after partial resection of renal clear cell carcinoma, such as trauma, herniated lumbar disc, kidney disease, etc. Patients need to go to the hospital in time for examination and treatment after clarifying the causes of the disease.