Cystosclerosis is treated conservatively with medications including doxazosin and tamsulosin hydrochloride. Cystosclerosis is a series of obstructive urinary disorders due to functional or organic lesions of the bladder neck. And it occurs most often in women over 30 years of age. It may be due to inflammatory, non-inflammatory, aging phenomena due to sphincter. Fibrous tissue sclerosis of the sphincter and its adjacent tissues. It is caused by prolonged spasm of the bladder neck. If the symptoms are mild, conservative treatment long-term anti-infective treatment can be carried out. The most commonly used drugs are levofloxacin, amoxicillin, and furazolidone. If there is a co-infection, the urine should be adequately drained. Antibiotics are then used for infection control. If low estrogen levels are present. Estrogen supplementation therapy may be performed. Do not self-medicate in the presence of cystosclerosis. Medical attention needs to be sought as soon as possible to avoid adverse complications.