There is no clinical evidence to prove the question of whether photorejuvenation can be done after HPV vaccination, and it is generally not recommended to do this program if there is a vaccine reaction such as rash or fever. The HPV vaccine, or cervical cancer vaccine, is indicated for the prevention of lesions, infections, etc., caused by the respective HPV types contained therein. Photorejuvenation is a non-exfoliating medical rejuvenation method, which mainly acts on the local skin and can promote the regeneration of local skin collagen, with effects such as whitening and wrinkle removal. After HPV vaccination, the body is in a special immune state, and it is generally recommended to carry out photorejuvenation treatment more than 1 week after injection. However, if the patient has adverse vaccine reactions such as rash, hives, fever, etc. after vaccination, photorejuvenation is no longer recommended in the short term to avoid aggravation of symptoms, etc. It is recommended that patients who are willing to undergo photorejuvenation treatment after HPV vaccination should go to regular medical institutions to avoid adverse consequences.