Alcohol should only be consumed at least one week after taking cephalosporin, because alcohol will produce a disulfiram-like reaction with cephalosporin antibiotics, and patients will experience flushing, palpitations, chest tightness, shortness of breath, nausea, vomiting, hypotension, shock and other manifestations, which can be life-threatening in severity. In addition to cephalosporin antibiotics, nitroimidazole antibiotics such as metronidazole, tinidazole and ornidazole can also produce disulfiram-like reactions with alcohol. Alcohol should only be consumed at least one week after the application of cephalosporin and nitroimidazole antibiotics, and alcohol consumption also needs to be followed by a week before the application of cephalosporin and nitroimidazole antibiotics. It is important to note that alcohol should be absolutely prohibited for one week before and after the application of medication, and it is important to ask in detail whether there is a history of alcohol consumption before the application of medication, which also includes alcohol-containing foods such as wine heart chocolate and alcohol-containing medications such as patchouli, which can produce disulfiram-like reactions with drugs such as cephalosporin and metronidazole.