Pimples in the eyes may be caused by blepharitis, conjunctival stones, and blepharospasmal cysts. 1. Blepharitis: If patients use dirty hands to rub their eyes for a long time, it may induce blepharitis, that is, suppurative inflammation of the eyelid glands, the patient’s eyelids may appear congestion, swelling, pain and other uncomfortable symptoms, the patient can follow the doctor’s instructions to use tobramycin eye drops and other medications to control inflammation and promote the recovery of the condition. 2. Conjunctival stones: Conjunctival stones may be associated with conjunctival inflammation, the formation of stones on the conjunctival surface of the eyelid, leading to acne in the eyes of patients, patients may experience foreign body sensation, photophobia, tearing and other symptoms. 3. Blepharophalangeal cyst: Blepharophalangeal cyst is a chronic inflammatory granuloma of the blepharophalangeal glands formed on the basis of obstruction of the blepharophalangeal gland drainage ducts and retention of secretions, and the patient’s eyelids may appear hard nodules, similar to pimples. It is recommended that patients with eyelid swellings seek prompt medical attention to evaluate their condition and follow medical advice.