Knee squatting pain walking without pain may be related to a variety of factors, such as chondromalacia patella, meniscus injury, rheumatoid arthritis, etc., should be directed to the symptoms of physical therapy, taking anti-inflammatory analgesic drugs, such as ibuprofen and other treatments to relieve symptoms. 1. Meniscus injury: generally caused by young patients after a large number of sports, squatting meniscus under increased pressure caused by pain. Mild injuries can be treated with hot compresses, massage, etc. If the condition is more serious, the affected limbs should be braked and bed rest. 2. Chondromalacia patella: generally is the knee long-term weight-bearing strain caused by joint degeneration, joint surface unevenness leads to pain when squatting. Patients should limit the knee joint strenuous activities, can be relieved by infrared, extracorporeal shock wave treatment. If the condition worsens, anti-inflammatory and analgesic drugs such as ibuprofen can be taken for relief. 3. Rheumatoid arthritis: it is caused by autoimmune disease of the patient, which can invade the knee joint and cause this symptom. Patients should rest in bed, rehabilitation training under the guidance of physicians, if necessary, can take anti-inflammatory analgesics such as ibuprofen, but also can take anti-rheumatoid drugs such as leflunomide and other treatment. There are many other factors that can cause this symptom, patients should go to the hospital in time for examination and receive appropriate treatment after clarifying the cause of the disease. The above medications should be taken under the guidance of a physician.