The following drugs can be taken for the treatment of sciatic nerve: first, non-steroidal anti-inflammatory drugs, such as loxoprofen sodium, celecoxib, ibuprofen extended-release capsules, indomethacin, naproxen, can promote the inflammatory response of sciatic nerve to subside and relieve the symptoms of nerve pain; second, drugs to eliminate edema of nerve, such as Mai Zhi Ling, Veritin, can promote the swelling of nerve to subside, restore the blood supply of nerve and improve the symptoms of nerve pain; Third, nerve nutrition drugs, such as vitamin B1, vitamin B6 and vitamin B12, can promote nerve damage repair and restore normal nerve conduction function. After comprehensive treatment with the above types of drugs, the inflammatory changes of sciatic nerve and pain symptoms can be significantly improved, and at the same time, attention should be paid to keeping warm to avoid pressure and strain on the nerve.