Softening foci in the left basal ganglia area cannot be treated well. Softening foci refer to a variety of destructive lesions that lead to necrosis and softening of brain tissue filled with cerebrospinal fluid, and the formation of cystic softening foci. Common reasons for the formation of softening foci in the left basal ganglia area include cerebral infarction, cerebral hemorrhage and other diseases. Once formed, softening foci are impossible to recover, so patients should prevent cerebral infarction. Usually, oral aspirin or Bolivar should be taken to prevent platelet aggregation, and other risk factors for cerebrovascular disease should be prevented and also treated, such as blood pressure, blood sugar, blood lipids and homocysteine control. If patients have atrial fibrillation, they must also prevent cardiogenic embolism leading to cerebral embolism by taking oral anticoagulants such as rivaroxaban and warfarin.