Pacemakers can be implanted with a picc tube, but care should be taken to place it through the subclavian vein on the opposite side of the pacemaker, with the tip of the picc located in the superior vena cava to avoid damage to the electrode. The implantation of the picc tube also needs to take a venous route, in the same direction as the axis of the pacemaker electrode. The implantation of the picc tube and the injection of drugs may cause damage to the electrode, resulting in the pacemaker not working properly. Pacemaker patients should pay attention to the following 2 points when implanting picc tubes. 1. When implanting a pacemaker, try not to go to the subclavian vein on the same side as the electrode, but to go to the subclavian vein on the opposite side of the pacemaker electrode, which can avoid causing damage to the electrode and lead wire. 2. The head end of the picc should be placed on the upper end of the superior vena cava, and try not to mix with the pacemaker lead to prevent direct damage to the pacemaker lead when injecting drugs. When implanting a picc tube in a patient with a pacemaker, it is important to thoroughly assess the condition and implant it under the operation of a specialized physician to avoid affecting the function of the pacemaker.