Pfizer and Watson 13-valent pneumonia vaccine can prevent 13 serotypes of pneumococcal infections, and their effects are similar, there is no saying which one is better. Pfizer 13-valent pneumonia vaccine is an imported vaccine, and its vaccination program is for infants and young children at the age of 2, 4, and 6 months for basic immunization, and 12 to 15 months of age for booster shots, it should be noted that more than 6 months of age has not yet been vaccinated with the first shot in the basic program is not recommended to continue to be vaccinated. Watson’s 13-valent pneumococcal vaccine uses tetanus toxoid as the protein carrier. After vaccination, it can also prevent pneumococcal infections of 13 serotypes: 1, 3, 4, 5, 6a, 6b, 7f, 9v, 14, 18c, 19a, 19f, and 23f, which are the same as those preventable by Pfizer 13-valent pneumococcal vaccine. Timely vaccination in accordance with the prescribed procedures can produce better protection, and both types of vaccines have guaranteed safety and efficacy and similar immunization effects.