Hidradenitis suppurativa is a chronic follicular occlusive disease that occurs in the folded areas of the armpits, groin, perineum, and perineum. Amoxicillin is not a first-line medication for the treatment of hidradenitis suppurativa; it can be used if the causative organism causing hidradenitis suppurativa is sensitive to amoxicillin, or not if it is not. Suppurative sweatitis occurs most often in young and middle-aged women and may be associated with more developed sweat glands. Excessive sweating, skin soiling, and scratching can be triggers for this disease, and if caused by a causative organism sensitive to amoxicillin, it can be taken against amoxicillin as prescribed by a doctor. Amoxicillin is suitable for sensitive bacteria caused by Streptococcus hemolyticus, Streptococcus pneumoniae, otitis media, sinusitis, pharyngitis, tonsillitis, genitourinary tract infections, skin and soft tissue infections, acute bronchitis, pneumonia, etc., and can also be used in conjunction with other drugs to eradicate Helicobacter pylori. Adverse reactions such as diarrhea, nausea, rash, reversible leukopenia, reversible thrombocytopenia and hemolytic anemia, urticaria and itching may occur after the use of this product, which usually resolves on its own. Adverse reactions such as prolongation of bleeding time and prothrombin time, allergic reactions, serum sickness, and allergic vasculitis may also occur, requiring discontinuation of the drug and prompt treatment. Nursing women should be cautious, allergic to penicillin and positive penicillin skin test is prohibited. Patients who want to take amoxicillin for suppurative sweatingitis treatment are advised to go to a regular hospital, consult a professional doctor, complete the relevant examinations, and avoid blindly using drugs.