Vaginal biopsy will definitely cause pain, the vagina is relatively rich in nerves and very sensitive, so there will be pain, but only a short period of time, because the biopsy speed is very fast, the pain will slowly disappear after the removal. After the biopsy, if there is active bleeding in the vagina, it is necessary to press the gauze to stop bleeding, if pressing the gauze to stop bleeding can not achieve the purpose of stopping bleeding, it is necessary to suture to stop bleeding and remove the stitches about 5 days after the operation. After the biopsy, it is recommended that: 1. keep the vulva locally clean to avoid pathogenic bacterial infection; 2. do not have sex within 15 days after the biopsy; 3. do not take a bath within 15 days after the biopsy to avoid localized infection of the wound; 4. do not take a bath within 15 days after the biopsy to avoid localized infection of the wound.