A small number of lymphocytes on lymphocentesis is not necessarily lymphoma.
The gold standard for diagnosis of lymphoma is pathological examination of lymph node biopsy. If only a few lymphocytes are seen in lymphocentesis, lymphoma cannot be clearly diagnosed, but the possibility of lymphoma cannot be completely ruled out either.
Therefore, in order to clarify whether it is lymphoma or not, it is recommended to remove the complete lymph nodes for pathological examination and immunohistochemical examination. Typical immunohistochemical findings of lymphoma are CD20(+), CD45(+), CD79a(+), Ki67(+), CD3(-) and so on.
It is recommended that the patient should go to the surgery for lymph node biopsy pathology examination in a timely manner. If the diagnosis of lymphoma is clear, it is necessary to go to the hematology department in a timely manner to improve the bone marrow aspiration and biopsy, PET-CT and other examinations to evaluate the condition, and to formulate an individualized treatment plan under the guidance of the physician and treat it aggressively.