The purpose of syphilis specific antibody measurement is to see whether there is syphilis infection, which may be a previous infection or a current infection. Syphilis is a sexually transmitted disease caused by syphilis spirochete infection, and specific antibodies will appear for a period of time after infection. Clinically, syphilis spirochete-specific antibodies are measured to determine whether or not there is syphilis infection. If there is syphilis infection, whether the patient has been cured or not yet cured, the serum of syphilis spirochete-specific antibody is positive. If the antibodies are negative, the patient may never have been infected with syphilis; there is also a possibility that the patient has been infected with syphilis but it is still in the incubation period, and the body has not yet formed antibodies, so it is recommended that the patient should be tested again three months after high-risk sexual contact.