The clinical symptoms of Empty Nose Disease include nasal obstruction, nasal dryness, nasal crust, olfactory disorder, generalized discomfort, psychological disorder and so on. 1. Nasal obstruction: Because of the decrease in the sensory function of airflow after the damage to the nasal mucous membrane receptors, the patient will have the feeling of nasal obstruction even if the nasal cavity is wide and the nasal cavity is free and there is no obstruction. 2. Nasal dryness, nasal scabs, olfactory disorder: the receptors and glands of the nasal mucosa are damaged, the nasal mucosa will feel dry, more nasal scabs, olfactory disorder and other symptoms. 3. Generalized discomfort: patients with empty nose will often feel pain in the nasal cavity, head and face. Some patients may have difficulty in breathing, or suffocation, and sleep may be affected. 4. Psychological disorders: due to the abnormal nasal symptoms, patients will have certain psychological impact, such as anxiety, fatigue, depression and other symptoms. Empty nose patients need to go to the hospital in time for examination and treatment to avoid delaying the condition.