The rash caused by efavirenz can go away on its own if it is mild, but if it is severe, it may not go away on its own and may need to be treated. 1. It can go away on its own: Efavirenz is an antiviral drug, mainly used in combination with other antiviral drugs. Adults, adolescents and children with HIV-1 infection who develop a rash after using Efavirenz are considered to be allergic to the drug, and if the symptoms are not particularly serious and the rash is only mild, the rash can go away on its own after discontinuing the use of the drug. 2. Can’t go away on its own: If the allergy is more serious after using efavirenz, and a severe rash appears or is accompanied by some other serious symptoms, the rash may not go away in this case, and you need to receive regular treatment. Each person’s constitution is different, the reaction after using the drug is also different, it is recommended to go to the hospital in time to minimize the adverse effects.