Patients with blistered and swollen lips can be clinically treated in different ways according to the causes of swelling: First, if the herpes is caused by herpes simplex virus infection, it can be treated by antiviral therapy, such as external application of aloesvir ointment and intravenous application of ribavirin injection, which can often achieve better treatment results. If the patient’s mouth is obviously swollen due to contact with allergens, the patient needs to stay away from allergens as soon as possible and take oral anti-allergy drugs such as loratadine, which can reduce the allergic allergic reaction in the body and relieve the swelling of the mouth. Third, if the patient has swelling and cyst formation inside the lips, it is possible that there is a mucous gland cyst, which needs to be surgically removed to avoid the progressive increase of the cyst. At the same time, it is necessary to keep the mouth clean to avoid mouth ulcers or infections, which can cause recurrent attacks of mouth swelling and blisters.