Herpes simplex virus infection causing blistering of the lips requires oral antiviral medication, such as Banlangen granules, antiviral oral solution, famciclovir and ganciclovir, etc. Local acyclovir ointment can be applied to the blistered lips for local antiviral treatment. If the blisters break down and cause local redness and vesicles, you need to apply erythromycin ointment locally for anti-inflammatory treatment. At the same time, avoid eating spicy and stimulating food, drink more water, take a light diet, and get enough rest and sleep to strengthen the body’s resistance. Blistered lips may also be labyrinthitis, for the cause of labyrinthitis take vitamins, zinc gluconate oral solution and iron supplement preparations, anti-allergy drugs and topical hormones, tacrolimus ointment, etc.