An iron nail in the foot usually requires a tetanus antitoxin injection to prevent tetanus. After a skin injury, if the wound is small and deep, it can easily lead to the growth of tetanus bacilli within the wound, which can lead to the formation of a tetanus infection. A wound formed by an iron nail sticking in the foot fits this scenario. Tetanus bacilli are widely found in nature, especially in soil, and are easily found in rust. Therefore, tetanus should be prevented routinely by injection of tetanus antitoxin if there is a break in the skin after a nail is stuck in the foot. If you are allergic to tetanus antitoxin, you can switch to tetanus immunoglobulin. Iron nails in the foot, it is recommended that patients seek medical attention in a timely manner, in addition to tetanus injection to prevent tetanus, but also need to avoid infection by timely debridement, and regular medication changes, taking antibiotics such as amoxicillin to prevent infection.