Middle-aged and old women with long spots on face consider freckles, chloasma and age spots. 1. Freckles: Freckles are caused by heredity and light, mainly distributed in the exposure area, the form of skin lesions is round, ovoid or irregular, usually pinpoint to rice grain size color, may be light brown to dark brown. 2. Chloasma: Chloasma is a kind of pigmentation spot, belonging to a subtype of skin melanosis, the rash is usually symmetrically distributed, which is very much related to sun exposure and endocrine secretion, and it mainly manifests itself as light brown to dark brown spots or patches, with clear boundaries and symmetrical distribution. 3. Age spots: age spots, also called seborrheic keratosis, is a kind of epidermal benign tumor, commonly seen in adults over 40 years old, and skin aging, heredity, gene mutation and other factors, the beginning of the light brown spots, and then gradually increase in size, deepen in color to dark brown or black. There may be other reasons for the spots on the face of middle-aged and old women, and it is recommended that those who are willing to be treated should go to regular hospitals, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of specialized doctors.