Initiative to make percutaneous vertebroplasty the first-line clinical treatment for vertebral compression fractures in the elderly

  1, the elderly vertebral compression fracture hazard.  The spine consists of 24 vertebrae, sacrum and tailbone, each vertebra is equivalent to a brick in the top pillar, the vertebral body is the “top pillar” of the human body – an important part of the spine, the elderly due to osteoporosis or tumor invasion, resulting in vertebral body compression strength A significant decrease in the compressive strength of the vertebral body due to osteoporosis or tumor invasion, minor weight bearing or falls, or even excessive bending can lead to a vertebral compression fracture. After the fracture of the main pillar of the human body, the main manifestation is pain in the lower back and limited movement, which is obvious when getting up and bending over, and serious fractures can lead to severe pain, affecting rest and life, as well as causing psychological damage to the elderly, manifesting a sense of helplessness and depression, and feeling disappointed with life.  2. Traditional treatment methods and deficiencies of elderly vertebral compression fractures.  The traditional treatment methods for elderly vertebral compression fractures are divided into two kinds of orthopedic surgery and conservative treatment. Surgical treatment includes internal fixation and spinal canal decompression, but most elderly people are in poor physical condition, with varying degrees of cardiovascular and cerebrovascular diseases, diabetes and other diseases of the elderly, can not withstand the massively invasive surgery, can tolerate surgery part of the patients due to osteoporosis, can lead to postoperative fixed screw loosening and displacement, re-operation caused by repeated injury. Therefore, in the past, most patients were treated conservatively, mainly by bed rest and symptomatic treatment with medication. According to the literature and our clinical follow-up observations, more than 60% of patients can develop post-fracture complications such as pneumonia, pulmonary embolism, decubitus ulcers, malunion, or chronic fractures due to poor healing, and a small number of patients can become disabled or even fatal.  3. The new perspective of minimally invasive interventional radiology on vertebral compression fractures in the elderly.  Interventional radiology is an emerging interdisciplinary discipline characterized by minimally invasive diagnosis and treatment of diseases, which has been flourishing worldwide in the past decade or so and has shown great vitality. Interventional radiology has abandoned the traumatic nature of traditional surgery and the long bed rest time of conservative treatment to address the characteristics of vertebral compression fractures in the elderly, and has adopted the reasonable principles of traditional surgery and conservative treatment, including fracture fixation, pain relief, and early activity. Based on the concept of humanistic care, interventional radiology advocates precise diagnosis, minimally invasive treatment, early treatment, early activity, elimination of pain, and humane treatment to improve the quality of life. At present, most experts in bone and joint interventional radiology call for interventional treatment methods to be the first-line clinical treatment for elderly vertebral compression fractures.  4. The methods and efficacy of interventional radiology in the treatment of compression fractures in the elderly.  One is Percutaneous Vertebroplasty (PVP), and the other is Percutaneous Kyphoplasty (PKP), which is developed on the basis of PVP. PKP is a new technique in which biomaterial (bone cement) is injected into the diseased vertebral body under real-time fluoroscopy to increase the compressive strength of the vertebral body, improve spinal stability, relieve or eliminate pain, and prevent the occurrence or development of vertebral collapse. The PKP technique involves percutaneous puncture of the vertebral body with a balloon or spreader to elevate the compressed vertebral body and then injecting the synthetic material (bone cement) into the diseased vertebral body under fluoroscopy under the guidance of imaging equipment. Both methods are currently widely used in clinical practice, each with its own advantages and disadvantages, and large-scale controlled studies are still underway. The clinical results of both methods have been satisfactory, with pain relief rates of over 90% for osteoporotic fractures and over 85% for tumor fractures, and over 90% of patients are out of bed after 2 days postoperatively.  According to the literature, vertebral fractures cost the government $15 billion each year, with 500,000 to 750,000 people in the United States each year. Shanghai, as an early aging city in China, is experiencing an increasing number of vertebral compression fractures caused by osteoporosis and tumors, with a total prevalence of 21% (15.58% for men and 23.45% for women) of osteoporotic fractures in the elderly in Shanghai alone, resulting in a huge medical burden on families and society. However, the society is still not aware of this, so we have to continue our efforts to promote the new technology of interventional treatment of bone and joint diseases for the benefit of the society through in-depth clinical and basic research.