Proteinuria showing two plus signs is a serious condition that indicates damage to kidney function and glomerular filtration. Under normal circumstances, protein is not filtered out of the body by the glomerulus, but is absorbed by the body to maintain the balance of the internal environment and provide energy for the body. A large amount of protein in the urine can lead to edema and malnutrition. If left untreated, it may lead to kidney failure, which in turn may lead to abnormalities in other organ functions and eventually lead to life-threatening conditions. The main diseases that cause proteinuria in humans are acute and chronic glomerulonephritis, tubular disease, nephrotic syndrome, hypertensive nephropathy, etc. It is recommended that patients go to the nephrology department of a regular hospital in a timely manner, improve the relevant tests, and actively treat the cause and symptoms.