In recent years, chronic kidney disease has raised the red light, and the prevalence is increasing year by year. Some data show that the global prevalence of the general population has reached 14.3%, and 10.8% for adults in China. Recently, the expert group of the Shanghai Chronic Kidney Disease Early Detection and Standardized Diagnosis and Treatment and Demonstration Project has developed new guidelines based on reference to foreign guidelines and combined with Chinese national conditions. The main points are as follows: 1. Chronic kidney disease is asymptomatic for a long time, and if it can be well controlled at an early stage, the disease can even be reversed. 2.Screening should be performed regardless of risk factors, and it is recommended that albuminuria and blood creatinine should be tested once a year. 3.High-risk groups include family history of kidney disease, diabetes, hypertension, hyperuricemia, advanced age (>65 years) and obesity, etc. Urine albumin/creatinine ratio and blood creatinine test should be performed at least once a year to estimate glomerular filtration rate (GFR). 4. Specific control goals for the progression of chronic kidney disease are as follows: (1) physical exercise at least 5 times a week for 30 minutes each time; (2) non-diabetic kidney disease should be treated with a low-protein diet starting from G3 stage; (3) salt <5g/d for adult patients with chronic kidney disease; (4) proteinuria target value should be controlled at urinary albumin excretion rate <30mg/d for patients with diabetic kidney disease and for non-diabetic patients, proteinuria (5) Maintenance of systolic blood pressure ≤140/90 mmHg for urinary albumin excretion rate (AER) ≤30 mg/d and ≤130/80 mmHg for AER>30 mg/d, regardless of whether diabetes is combined; (6) HbA1c target value of 7.0%, shorter life expectancy, presence of (7) Lipid control target, which should be assessed according to the risk of disease; (8) Blood uric acid <300 μmol/L for those with gout onset, and intervention when blood uric acid is >480 μmol/L for those with secondary hyperuricemia. 5, GFR <45 mL/(min-1.73m2), drugs with potential nephrotoxicity and renal excretion, such as RAS system blockers, diuretics, NSAIDs, metformin, digoxin, etc., should be suspended. 6, chronic nephropathy anemia: for non-dialysis anemic adult patients who are not given iron therapy, such as transferrin saturation ≤ 30% and ferritin ≤ 500 g/L, it is recommended to give 1~3 months of oral iron therapy. 7. Dialysis treatment should usually be started when there are clinical manifestations and signs of uremia and eGFR decreases to 5~8 mL/(min-1.73 m2).