Small pits on the calves may be edema or depressed scarring. 1. Edema: If small pits appear on the legs when pressed, it is a manifestation of depressed edema, which may be caused by physiological factors, drug factors, heart and liver and kidney diseases and other pathological factors. (1) Physiological factors: prolonged sitting or standing will cause depressed edema of the calves, which is manifested as small pits on the calves; women will store more fluids in their bodies when they are pregnant, so depressed edema of the calves often occurs. (2) Drug factors: some drugs for high blood pressure can cause sunken edema, such as Benadryl; estrogen tablets and ibuprofen and other drugs can also cause sunken edema of the calves. (3) Disease factors: patients with cardiac and renal insufficiency can often have lower leg edema. 2. Depressed scar: also known as atrophic scar. If trauma, folliculitis, boils, carbuncles and other lesions have occurred in the calf area, depressed scar can be formed in the local area after the injury has healed. This kind of scar formation is lower than the surrounding skin, manifested as having small pits. The pits formed by depressed scarring are persistent and are not related to pressure. Small pits on the calf can also be caused by other reasons, it is recommended to consult a doctor in time, and follow the doctor’s instructions to carry out the appropriate examination, to clarify the cause of the disease and then treatment.