The biggest danger of gastric polypectomy is gastric perforation resulting in diffuse peritonitis. After the removal of gastric polyps, first of all, it may cause bleeding in the patient’s wound area, and secondly, for some patients, if the base of the polyp is deeper and larger, then the scope of the polyp removal will increase accordingly, which may lead to gastric perforation, resulting in the development of diffuse peritonitis. After removal of gastric polyps leading to gastric perforation, the patient may experience distension and cramping in the left upper abdomen, middle and upper abdomen, and may even cause severe peritonitis. In addition, when the peritonitis is severe, the patient may go into shock due to the severity of the infection. After gastric perforation, effective measures should be taken promptly for treatment, and patients should be given continuous gastrointestinal decompression and drainage. If the patient’s condition is critical, timely surgical treatment should be taken. After gastric polypectomy, patients need to be closely observed for any discomfort symptoms, and consult the doctor in time to avoid delayed treatment.