The Down’s syndrome test for trisomy 21 is high risk, but the non-invasive DNA test is low risk, which can initially rule out the risk of chromosomal developmental abnormality; to be on the safe side, further amniocentesis can be considered. Amniocentesis is a test that requires the extraction of about 20 ml of amniotic fluid between the 16th and 24th weeks of pregnancy for further analysis to determine whether there is a possibility of chromosomal abnormalities in the fetus. The amniocentesis test provides more accurate results and analyzes more compared to non-invasive DNA testing. If the financial situation permits, amniocentesis can be considered for further examination. In addition, because of the current level of operation, the chance of complications after amniocentesis test is relatively low, so there is no need to worry about this aspect. During pregnancy, it is important to take pregnancy tests on time to understand the development of the fetus, and if there is any discomfort, it is necessary to seek medical advice and consult a specialist for guidance.