The key to eradicating acne, also known as sebaceous cysts, is to remove the cysts completely; topical medications are usually ineffective. If the cyst is infected, antibiotics can be given. The cause of sebaceous cysts is clear: they are caused by blockage of the sebaceous ducts and localized accumulation of sebaceous secretions. Smaller cysts are usually asymptomatic. Larger cysts can be raised above the surface of the skin. Pressure on the tissue can cause pain. Complicated infections may cause redness, swelling, and pus. If accompanied by bacterial infection, you can follow the doctor’s instructions to use topical mupirocin ointment, oral cefadroxil and other drugs, which have anti-inflammatory and reduce redness and swelling. Disease treatment is mainly based on surgical excision treatment, such as cystectomy, which can completely remove sebaceous cysts. In summary, topical medications are generally not useful in the treatment of sebaceous cysts. It is recommended to go to the dermatology department of the hospital or surgical excision treatment at a later date.