1. Early menarche: the average age of menarche was 14-15 years old, but now it is as early as 9 years old, and the average age is 10-13 years old 2. Late menopause: menstruation is more than 35 years old 3. High age of first birth, more than 35 years old 4, high fat, high protein diet and obesity: subcutaneous fat can be transformed into estrogen, breast cancer is a hormone-dependent malignant tumor, the occurrence and growth of tumors are closely related to hormones, and excessive secretion of estrogen can lead to breast cancer Xiang Nan, Department of Traditional Chinese Medicine, Affiliated Hospital of Guizhou Provincial Center for Disease Control and Prevention 5, lifestyle habits: drinking, smoking, coffee 6, heredity: family history 7 8.Spiritual stimulation, excessive stress