High platelets are generally not leukemia, because platelets tend to be reduced in patients with leukemia, but there are a small number of patients with leukemia whose platelets can be normal. The platelets are high depending on the degree of high, normally the reference value of platelets is (100-300) × 10^9/L, if the platelets are high, but less than 450 × 10^9/L do not need further treatment, regular observation can be. If the platelet count is higher than 450×10^9/L, you should consult a hematologist for relevant tests such as bone marrow aspiration, bone marrow biopsy, and genetic tests to further clarify whether it is primary or secondary thrombocythemia. For patients with high platelets there is a certain risk of thrombosis, and oral aspirin should also be taken to prevent thrombotic events. Aspirin is contraindicated if the platelets are abnormally high, greater than 1500 x 10^9/L, as the risk of bleeding is predominant at this time.