The diagnosis of leukemia is generally not made solely on the basis of the number of naïve cells, but requires a comprehensive analysis based on the patient’s other symptoms and test results.
Abnormal numbers of naïve cells can be seen in a variety of diseases, not only in leukemia. When the body has a serious infection, incompletely matured naive leukocytes are released from the bone marrow early, which can lead to an increase in the proportion of naive cells in the blood, as well as a significant increase in the proportion of naive cells in the peripheral blood if the body has other malignancies. In normal people, the percentage of infantile cells in the bone marrow does not exceed 5%, and if it exceeds 30% combined with symptoms of fever and anemia, the initial diagnosis of leukemia can be made.
Therefore, it is recommended that patients with an abnormal number of infantile cells should not be overly nervous and should be seen by the hematology department when they develop obvious symptoms.