Sweating is the body’s normal metabolic activity, people in the exercise, the heat of the day, nervousness, easy to sweat, but some people even in the cold days, sweaty palms and feet will be easy to sweat. This abnormal performance has brought them a great deal of trouble. In fact, sweaty palms and feet are very likely to have hand sweating, today, I will tell you about hand sweating. Hand sweating, is a disease of hypersecretion of sweat glands in the hands, mainly manifested as sweaty palms, but also some patients are also accompanied by sweaty armpits, sweaty feet and sweaty head and face. According to the cause of hand sweating, it can be categorized into primary hand sweating and secondary hand sweating. Primary hand sweating is caused by excessive sympathetic hyperactivity, which is present in the vast majority of people with hand sweating. Secondary hand sweating is a small number of people who experience increased sweating due to a medical condition. Examples include hyperthyroidism, endocrine disease, mental illness, tumors, and endocrine imbalance during menopause. Primary hand sweating is categorized as mild, moderate, or severe depending on the degree of sweating, with mild cases having moist palms, moderate cases having sweaty palms soaking a handkerchief, and severe cases having sweaty palms in the form of beads. Among them, moderate and severe hand sweating will affect the patient’s work, study, life and socialization, and will bring great distress to the patient. For example: 1. the keys used will be rusty. 2. in writing will be wet through the paper. 3. hold the child to hold unstable, afraid of falling on the ground. 4. encounter acquaintances or friends, afraid to shake hands with him, deliberately pretending not to see, etc.. So the more serious hand sweating needs to be treated in a timely manner, to avoid bringing more trouble to the future life. At present, the treatment of primary hand sweating is mainly divided into non-surgical treatment methods and surgical treatment methods. Non-surgical treatments mainly include local application of antiperspirant drugs, iontophoresis, oral anticholinergic receptor blockers, etc. Surgical treatments are minimally invasive techniques of fluorescence visualization ETS. Non-surgical treatments are difficult to cure primary hand sweating, and can only play a role in alleviating the problem, while the minimally invasive fluoroscopic ETS technique can effectively cure primary hand sweating.