Peeling of skin around the mouth may be caused by physiological factors such as dry air, or it may be related to pathological factors such as perioral dermatitis, contact dermatitis and vitamin deficiency. 1. Physiological factors: such as air dryness, infrequent drinking of water may cause peeling around the mouth, which is a normal phenomenon, drink more water, use a humidifier if necessary, the symptoms can be gradually relieved. 2. Pathological factors (1) Perioral dermatitis: an inflammatory disease, caused by the long-term use of fluoride toothpaste, topical glucocorticoids, excessive use of cosmetics and other factors, can be manifested as perioral diffuse erythema, skin dryness, swelling and other symptoms, which can be accompanied by perioral peeling, itching and other symptoms. (2) Contact dermatitis: contact around the lips with lipstick, lipstick, etc. causes perioral allergy, metamorphic reaction, symptoms of perioral peeling, mostly accompanied by itching. (3) Lack of vitamins: mostly seen in partial or picky eaters, do not often eat fresh fruits and vegetables, caused by the body of vitamin A, B and other deficiencies, resulting in dryness and peeling of the skin around the mouth. If the symptoms of peeling skin around the mouth and long-term non-relief, it is recommended to go to the hospital in a timely manner to identify the cause of active treatment, so as not to delay the condition.