The difference between Spleen and Kidney Two Helping Pills and Spleen and Kidney Two Replenishing Pills lies in the composition, efficacy and main treatment. 1. Difference in composition and efficacy: Spleen and Kidney Double Booster Pill is composed of maitong, codonopsis, soft-shelled turtle, wolfberry, yujin, tangerine peel, and hen’s inner gold, etc. Its efficacy is to strengthen the spleen and benefit the qi, nourish the liver and kidneys. Spleen and Kidney Double Replenishing Pill is composed of Radix et Rhizoma Ginseng, Fructus Schisandrae Chinensis, Rhizoma Cinnamomum Cassiae, Radix et Rhizoma Ophiopogonis, Radix Astragali, Semen Coix Seed, Radix Achyranthis Bidentatae, and its effects are to invigorate the spleen and open the stomach, and nourish the liver and kidney. 2. Difference in treatment: Spleen and Kidney Pills treat weakness of the spleen and kidneys caused by weakness of the qi and weakness, body fatigue, not thinking about food, stomach and epigastric congestion, lumbar and knee soreness, dizziness and tinnitus. Spleen and Kidney Double Supplement Pill is used for treating deficiency of the spleen and kidney, deficiency of qi and yin, loss of appetite, yellow face and thin muscles. The adverse reactions of Spleen and Kidney Double-Heat Pill and Spleen and Kidney Double-Heat Pill are not clear, forbidden for pregnant women, avoid greasy food, and not suitable for those who have external sensation or solid internal heat. Drugs must be used under the guidance of a doctor, do not blindly self-medication, in order to avoid affecting the health of the body.