Many young and middle-aged people, due to the stress of work, low activity; measured blood pressure systolic pressure is normal, diastolic pressure is higher than 90 mm Hg, sometimes the pulse pressure difference is very close, such as: 130/110 mm Hg, the patient subjectively feel dizzy, chest discomfort. This is due to increased sympathetic nerve activity and increased peripheral vascular resistance. It is the early stage of hypertensive disease. Since the prognosis is better in middle-aged people with purely elevated diastolic blood pressure in the near future, is it possible to avoid treatment? No! Simple diastolic hypertension should not be neglected, because with the prolongation of the disease, simple diastolic hypertension can transform into classical hypertension. It may even progress to pure systolic hypertension. If left untreated, the prognosis is poorer with ageing. Therefore treatment, both pharmacological and non-pharmacological, is administered at an early stage. High diastolic blood pressure is caused by atherosclerosis, and only vascular softening treatment is the fundamental measure to lower diastolic blood pressure, so it is recommended to continue antihypertensive treatment with additional vascular softening drugs, such as rutin and vitamin E, for better therapeutic effect. Blood pressure formation depends on 5 factors: the elasticity of large blood vessels, the contraction ability of the heart, the viscosity of blood, and peripheral vascular resistance. The heart contracts to form systolic pressure, the large arteries retract to form diastolic pressure, and the most important factor affecting diastolic pressure is peripheral vascular resistance. In primary hypertension, it is mainly the smaller caliber of resistance vessels and the increase of pressure-raising substances that cause higher peripheral vascular resistance, resulting in higher diastolic blood pressure. Cerebral ischemia, high-salt diet, and stress all lead to sympathetic excitation, which promotes the release of norepinephrine and activates the renin-angiotensin-aldosterone system, causing vasoconstriction and increased peripheral resistance, resulting in increased diastolic blood pressure. Patients with high diastolic blood pressure should be reminded to: 1. adhere to drug therapy, while adjusting their lifestyle, limiting smoking and alcohol, and physical exercise. 2, drug dose maintenance after a period of time can be reduced to observe, such as blood pressure can still be maintained at normal levels, can be maintained at the lowest dose of normal blood pressure is ideal, but do not easily stop the drug. The treatment of patients with increased diastolic blood pressure alone should be β-blockers as the first choice, followed by angiotensin-converting enzyme inhibitors, angiotensin receptor antagonists drugs. If the effect of antihypertensive drugs is not satisfactory, you should go to the cardiology department of the hospital and ask the specialist to adjust the antihypertensive drugs.