Lupus erythematosus generally refers to systemic lupus erythematosus (SLE), which can gradually develop into lupus nephritis after involving kidneys. Lupus nephritis lacks an effective cure, so it cannot be restored to normal in general, but it can be effectively controlled by standardized and timely treatment to slow down the progression of the disease and further damage of renal function. Lupus nephritis is a disease in which SLE involves both kidneys and causes abnormal renal function, which can cause proteinuria, hematuria, edema and other symptoms. According to the type of pathology, it is mainly classified into lupus nephritis type I~VI, among which type I lupus nephritis has a better prognosis, while type V and VI have a worse prognosis, which may affect the life expectancy and the quality of life of the patients if not treated in a timely manner. The treatment of lupus nephritis is still based on medication, daily care and renal replacement therapy. Although there is no effective cure for the disease, active treatment can effectively alleviate the development of the disease. It is recommended that SLE patients go to the rheumatology and immunology departments of regular hospitals for timely consultation and standardized diagnosis and treatment according to the doctor’s instructions, so as not to aggravate their conditions.