Foot pain after fever in children may be caused by high fever leading to increased metabolism of the body, which needs to be treated with rest, through the use of medication, and so on. It is also important to consider diseases such as juvenile idiopathic arthritis, which are often treated with general therapy and medication. Children’s foot pain after fever may be due to the high fever caused by the body’s metabolism increased, the foot muscle decomposition and metabolism of a large number of lactic acid, resulting in the emergence of foot pain. This condition can be treated with medications such as acetaminophen and ibuprofen to lower the body temperature, and the foot pain may improve as the body temperature drops. Juvenile idiopathic arthritis can also occur. This is a connective tissue disease of undetermined etiology, requiring bed rest during the onset of the disease, and encouraging children to participate in appropriate exercise during the remission period. Ibuprofen, methotrexate, hydroxychloroquine and other medications should be used when necessary. Parents are advised to bring their children to the doctor to complete the relevant examinations and standardize the treatment once they find children with fever. In addition, the above drugs should be used under the guidance of a doctor, do not blindly use drugs.