Cleft palate occurs when the lateral palatine processes and the nasal septum do not fuse or do not fuse at all due to certain factors during embryonic development. A cleft palate occurs when the lateral palatine processes and septum are not fused or partially fused during fetal development, especially during the first 12 weeks of development, due to genetic, nutritional, endocrine, pharmacologic, physical, and alcohol and tobacco influences. Cleft palate can occur unilaterally or bilaterally, with eighty percent of patients having unilateral or bilateral cleft lips. During pregnancy, women need to receive relevant knowledge to pay attention to nutrition, avoid mental overstress and fatigue, quit smoking and drinking, avoid infections, and take regular pregnancy checkups.