Thyrotropin 10.6mIU/L is on the high side, need to take medication under the guidance of a doctor, usually patients need to take medication all the time to replace the treatment. Thyroid stimulating hormone 10.6mIU / L, high, if T3, T4 normal, suggesting subclinical hypothyroidism, subclinical hypothyroidism will affect lipid metabolism, increase the risk of atherosclerosis and myocardial infarction, TSH is greater than 10mIU / L need for thyroid hormone replacement therapy, a small portion of the TPO antibody-negative subclinical hypothyroidism can be restored, the majority of patients need to be always on drugs to replace the therapy. Thyroid stimulating hormone 10.6mIU/L, if previously T3, T4 decline, diagnosed as clinical hypothyroidism, then generally need to take medication all the time. Thyroid-stimulating hormone 10.6mIU/L should be treated according to the condition as prescribed by the doctor.