Itchy calves are not necessarily a precursor of cancer. There are many reasons that can cause itchy calves, such as dry skin can cause itchy skin; neuropsychological factors such as mental tension, anxiety, depression, etc., can also cause itchy calves. Then there are some systemic diseases, such as uremia, hyperthyroidism, diabetes, connective tissue disease, AIDS, etc. can also cause itchy calves, and then there is local inflammation or allergies in the calves, which can also cause itchy calves. Of course, lymphoma, leukemia and other malignant tumors may also cause itchy calves. So if you have itchy calves it is best to go to the hospital for an examination to find out the cause of itchy calves, and then carry out targeted treatment according to the cause.