Plasma exchange can be used in the treatment of kidney disease, blood disease and other related treatments, which can slow down the progress of the disease, improve the quality of life, prolong the survival period and so on. Plasma exchange refers to the process of discarding the patient’s plasma while replacing it with plasma from a healthy person. 1. It is used for rapidly progressing renal failure, which can slow down the degree of renal function damage and improve the quality of life. 2. It is used for hypercholesterolemia patients to slow down the burden of metabolic function of the patient’s body and reduce atherosclerosis. 3. It can be used in the treatment of acute poisoning to save life. 4. It can be used for various emergency treatments encountered by leukemia patients in the clinic, such as the use of CarT cells to treat acute lymphoblastic leukemia, when there is a storm of inflammatory factor, it can be used for emergency plasma exchange to reduce the level of inflammatory factor and save lives. Plasma exchange is a rapidly evolving technique that is valuable in the treatment of many diseases. However, there are complications such as allergic reactions and infections, but it is safer as long as it is prepared in advance and under the guidance of a medical professional.