Over-exercise knee pain can be caused by a fatiguing injury to the soft tissues around the knee, or it can be due to a meniscus injury. Relief methods include physical therapy, medication and surgery. 1. Soft tissue injury: patients need to brake the affected limbs after the symptoms appear, and if the conditions permit, ice can be used to apply ice compresses, and at the same time elevate the affected limbs to promote the contraction of small blood vessels; after 72 hours of relief period can be changed to hot towels; if the pain symptoms are obvious, you can take oral meloxicam, loxoprofen, and other medications to relieve the symptoms. 2. Meniscus injury: Excessive exercise may lead to meniscus injury or tear, knee pain. Patients need to improve the magnetic examination of the knee joint to clarify the meniscus damage, if the damage is mild, you can choose the conservative treatment of plaster or support fixation; if the damage is more serious meniscus tear, it is recommended to carry out meniscus repair or reconstruction surgery under the knee arthroscope. Exercise excessive knee pain may also have other reasons, even if the same disease, the patient’s physical condition is different, different stages of the disease, the treatment method is different, should be standardized under the guidance of the doctor treatment. All of the above medications should be used under the guidance of a doctor, avoid self-medication.