Progesterone is very effective in treating menstrual disorders caused by luteal insufficiency, such as shortened menstrual cycles or irregular vaginal bleeding in the second half of menstruation, and is often given after ovulation. For menstrual disorders caused by estrogen deficiency, the effect of progesterone treatment is not good, such as menstrual dribbling with progesterone treatment, can not achieve satisfactory results. For menstrual disorders, the first thing to do is to find out the cause, and then give treatment according to the cause. For premature atrophy of the corpus luteum, resulting in luteal insufficiency, the clinic can use progesterone to give treatment, which will achieve more satisfactory results.